Analytical Project Leader

Analytical Project Leader (m/f/d): Analytical Development / Drug Substances / Mass Spectrometry / peptide chemistry / HPLC / UPLC/ ICH / Analytical Methods / English

Project: For our client based in Basel, we are looking for Analytical Project Leader

Background:
The Analytical Research & Development department, an integral component of Synthetic Molecules Technical Development, bears global responsibility for the advancement of cutting-edge analytical methodologies, the comprehensive analysis of raw materials, intermediates, active pharmaceutical ingredients, and various dosage forms pertaining to synthetic molecule development products, and the meticulous preparation of regulatory documentation for submission to health authorities.

In this role you will be joining a highly motivated and experienced team of analytical scientists. You will be responsible for leading analytical development activities for synthetic molecule projects, from early development to commercialization. This is an exciting opportunity to apply your expertise in a dynamic and challenging environment, contributing to the development of life-changing medicines.

The perfect candidate holds a Master's or Ph.D. in chemistry or pharmacy, coupled with a minimum of three years of experience within the pharmaceutical industry as an analytical project lead. A robust background in analytical development is paramount, with particular expertise in liquid chromatography and diverse
detection methodologies. Beyond technical proficiency, the person is an open-minded, goal-oriented individual who demonstrates the ability to thrive within a dynamic environment. The perfect candidate perceives challenges as opportunities for collaboration and consistently exhibits respect with team members, customers, and stakeholders. Furthermore, an excellent command of the English language is a prerequisite.

Tasks & Responsibilities:
The Analytical Research & Development department is a key part of Synthetic Molecules Technical Development. It is globally responsible for advancing analytical methodologies, performing in-depth analyses of active pharmaceutical ingredients, and diverse dosage forms, as well as preparing detailed regulatory documentation for submission to health authorities. In this role, you will join a motivated and experienced team of analytical scientists. You will lead the analytical development of synthetic molecule projects involving peptides, from early development to commercialization. This role offers a unique opportunity to apply your expertise in a dynamic, fast-paced environment and contribute to the development of life-changing medicines.
? Developing a phase-appropriate control strategy for drug substances and drug products.
? Collaborating effectively with stakeholders across various departments.
? Coordinating comprehensive analytical activities, which involves generating physical and chemical data for materials, developing/improving and validating analytical test methods or other analytical controls and ensuring thorough documentation, timely delivery and adherence to quality standards.
? Coaching technicians and junior scientists on project work and serving as a central point of contact for project-related information.
? Conduct work in compliance with cGMP where applicable, safety, and regulatory requirements.
? Supervise internal laboratory activities and / or testing activities at CLOs/CDMOs.
? Plan and document experiments/results independently and prepare for regulatory submissions such as IND and NDA.

Must Haves:
? A Master's or Ph.D. in chemistry, pharmacy, or a related field.
? At least 3 years of professional experience (industry-based) in analytical development of drug substances and products for peptides.
? In-depth knowledge of peptide chemistry, including synthesis, purification, and characterization.
? Expertise in key analytical techniques such as High-Performance Liquid Chromatography (HPLC), Ultra-Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS) for peptide analysis.
? Proven experience in developing and validating ICH-compliant analytical methods.
? Proficiency in degradation and stability studies for peptide, including forced degradation and impurity profiling.
? Understanding of key requirements for peptide drug substances and/or drug product specifications.
? Strong knowledge of peptide degradation pathways.
?A strong quality mindset and excellent attention to detail.
? Digital savvyness to support digital transformation initiatives; familiarity with statistical analysis of analytical data is also advantageous.
?Open-minded, goal-oriented, and able to work in a fast-developing environment.
?Takes challenges as opportunities and is able to respectfully collaborate with team members, customers and stakeholders, even in stressful situations.
?Excellent command of the English language.

Nice to Haves:
?Additional experience in analytical development with oligonucleotides or
biologically derived molecules is a plus.
? Proficiency in German is considered a plus. Extended skills for liquid formulations are considered as a plus:
? Understanding of the physicochemical properties of peptides and how they impact formulation development.
? Skilled in conducting systematic stability studies for peptides in liquid formulations under various conditions.

Reference Nr.: 924710
Rolle: Analytical Project Leader
Industry: Pharma
Location: Basel
Pensum: 100%
Start: ASAP (Latest start date 01.04.2026)
Duration: 12++ Months
Deadline: 26/01/2026

If this position has piqued your interest, please send us your complete resume. If this position does not quite match your profile and you would like to receive other positions directly, you can also send us your resume via this ad or to jobs[at]itcag[dot]com.
Contact us for more information about our company, our positions, or our attractive payroll-only program: +41 41 760 77 01.
About us:
ITech Consult is an ISO 9001:2015-certified Swiss company with offices in Germany and Ireland. ITech Consult specializes in placing highly qualified candidates for temporary staffing in the fields of IT, life sciences, and engineering. We offer temporary staffing and payroll services. This is free of charge for our candidates, and we do not charge any additional fees for payroll services.